Experiência pública

Molecular signaling of osteoporosis

Molecular signaling in osteoporosis involves pathways that regulate bone remodeling. Key players include RANKL, which promotes bone resorption by activating osteoclasts, and OPG, which inhibits this process. An imbalance, often due to hormonal changes or aging, leads to increased bone resorption and decreased bone formation, resulting in weakened bones. Understanding these molecular signals helps in developing treatments for osteoporosis.